12/08/2005 | Formation of Bromate Ion from Application of Dihalodialkylhydantoin Sanitizers (BCDMH and DBDMH) into Swimming Pools and Associated Cancer Risks for Swimmers. DP Barcode 324327. (PDF, 14 pp, 739K) | Tim Leighton | Antimicrobials Division | - |
08/28/2000 | 5,5-Dimethylhydantoin - Revised Report of the Hazard Identification Assessment Review Committee. Tox review 014298. (PDF, 18 pp, 1MB) | Timothy McMahon | Risk Assessment & Science Support Branch | - |
08/14/2000 | 5,5-Dimethylhydantoin - Report of the Hazard Identification Assessment Review Committee. Tox review 014292. (PDF, 18 pp, 1MB) | Timothy McMahon | Risk Assessment & Science Support Branch | - |
07/14/1999 | Efficacy Review and Label Review for "Dantabrom TBS-5B", for "Dantabrom TBS-4A", and for "Dantabrom TBS-5A" EPA Reg. No(s) 6836-ETU, 6836-ETE and 6836-ETG. MRID 44801904 & -05. [in-tank sanitizing data]. (PDF, 3 pp, 178K) | Bruce Mann | Efficacy & Science Support Branch AD | 44801904... [More] |
07/10/1997 | BCDMH. Review of Toxicology Data. Combined chronic/oncogenicity feeding - Rat. (83-5) MRID 44095901. (PDF, 34 pp, 2MB) | Raymond Locke | Toxicology Branch | 44095901 |
01/29/1997 | 1-Bromo-3-chloro-5,5-dimethylhydantoin: Review of toxicology data. 18-month oncogenicity study in mice, 83-2b. MRID 44063901. Tox review 012154. (PDF, 15 pp, 892K) | Raymond Locke | Toxicology Branch | 44063901 |
01/29/1997 | 1-Bromo-3-chloro-5,5-dimethylhydantoin (BCDMH). Addenda to Data Evaluation Records (DERs). [Addenda to Doc. No. 011997 and 011546.] MRID 44111900, 44111901, 44111902. Tox review 012153. (PDF, 3 pp, 129K) | Raymond Locke | Toxicology Branch | 44111900... [More] |
10/23/1996 | Review od Chronic (One-Year) Feeding Study in the Dog Supporting the Reregistration of 1-bromo-3-chloro-5,5- dimethylhydantoin, Case # 3055, AI 006315. (PDF, 16 pp, 970K) Attachments | Kathleen Depukat | Accelerated Reregistration Branch SRRD | - |
07/24/1996 | 1-Bromo-3-chloro-5,5-dimethylhydantoin: Review of Toxicology Data. Subchronic oral toxicity (feeding) - Dog; Range-finding study for chronic toxicity - Dog. MRID 43553101. Tox review 011997. (PDF, 12 pp, 795K) | Raymond Locke | Toxicology Branch | 43553101 |
07/09/1996 | BCDMH. Review of Toxicology Data. Multigeneration Reproduction - Rat (83-4). MRID 43290601. Tox review 011975. (PDF, 26 pp, 2MB) | Raymond Locke | Toxicology Branch | 43290601 |
05/19/1995 | EPA ID # 006315: 5,5-Dimethylhydantoin (DMH) - -Review of Carcinogenicity Study in Mice and Chronic Toxicity/Caarcinogenicity Study in Rats (MRID No. 433977-01 and -02). Tox review 011556. (PDF, 33 pp, 2MB) | Paul Chin | Toxicology Branch | 43397701... [More] |
05/12/1995 | 5,5-Dimethylhydantoin. Review of Toxicology Data. MRID 43553101. Chronic (One-Year) Toxicity (Dog). Tox review 011546. (PDF, 16 pp, 1011K) | Raymond Locke | Toxicology Branch | 43553101 |
05/12/1995 | EPA ID # 006315: 5,5-Dimethylhydantoin (DMH)- Review of 90-Day Subchronic Dermal Toxicity Study in Rats (MRID No. 431739-01). Tox review 011544. (PDF, 14 pp, 712K) | Paul Chin | Toxicology Branch | 43173901 |
02/15/1995 | Review of three acute estuarine toxicity tests for Halobrom (DP Barcode D171469). MRID 420761-02, -01, -03. (PDF, 4 pp, 213K) | Anthony Maciorowski | Ecological Effects Branch | 42076101... [More] |
01/12/1995 | Review of product chemistry and toxicology studies for the chemical 1-Bromo-3-chloro-5, 5-dimethyllhydantoin. (PDF, 2 pp, 116K) | Mark Wilhite | Accelerated Reregistration Branch | - |
09/15/1994 | Product Chemistry Review of Halobrom (RR Case#3055, Phase 4) Page 3 removed, quality control procedures. (PDF, 3 pp, 131K) | Alfred Smith | Registration Support Branch | - |
05/13/1994 | EPA ID # 006836: Registrant's Response to Agency Review of MEH (5-methyl-5-ethylhydantoin) General Metabolism Study. MRID 430204-02. Tox review 010966. (PDF, 2 pp, 131K) | Paul Chin | Toxicology Branch | 43020402 |
09/27/1993 | Review of data for hydantoin submitted by Lonza Inc. Flow-through life-cycle toxicity. Daphnia magna. Early life-stage toxicity. Fathead minnow. Pages 15-22, 37-40 removed, registrant data. MRID 42721701, 42721702. (PDF, 55 pp, 2MB) | Anthony Maciorowski | Ecological Effects Branch | 42721701... [More] |
03/20/1993 | EFED's comments on dihalodialkylhydantoins DCI (Case 3055). (PDF, 1 pp, 43K) | Bernice Slutsky | Environmental Fate & Effects Division | - |
08/27/1992 | Lonza Inc.; List C Phase IV. MRID 930760-02, -03, 04, 05, 20, 06, 27, 07, 22, 08, 09, 10. (PDF, 48 pp, 2MB) | Douglas Urban | Ecological Effects Branch | 93076002... [More] |
03/30/1992 | ID No.: 006836-00115, Metabolism Studies with Dimethylhydantoin in Rats. MRID 42173901. Tox review 009394. (PDF, 22 pp, 1MB) | Melba Morrow | Toxicology Branch | 42173901 |
01/07/1992 | ID No.: 006836-00115, 90 Day Subchronic Oral Study in Rats with Dimethylhydantoin. MRID 42009201. Tox review 008972. (PDF, 9 pp, 460K) | Melba Morrow | Toxicology Branch | 42009201 |
05/21/1990 | Submission of estuarine data to support proposed label amendment for once-through use in industrial cooling water systems. Pages 13-14 removed, registrant data. MRID 409931-01, -02, -03. (PDF, 14 pp, 646K) | Curtis Laird | Ecological Effects Branch | 40993101... [More] |
05/21/1990 | Submission of estuarine data to support proposed label amendment for once-through use in industrial cooling water systems. Pages 7-8 removed, registrant data. MRID 409931-01, -02, -03. (PDF, 14 pp, 657K) | Curtis Laird | Ecological Effects Branch | 40993101... [More] |
01/16/1990 | Reg. Nos. 5785-65 and 5785-63. BromoCide Tablets, BromoCide Granules. Review Amendment Request for Additional Use Pattern and Additional Brand Name (BromoCide Tablets and Granules) (PDF, 6 pp, 1002K) Attachments | Paul Mastradone | Chemistry Review Section | - |
08/23/1989 | Dantobrom S; EPA ID # 6836-116; Record No. 245107. MRID #s 410889-01, -02 Tox review 007447 (PDF, 3 pp, 144K) | Joycelyn Stewart | Toxicology Branch | - |
04/05/1989 | File or Reg. No. 5785-IU. Proposed registration of uses in brewery pasteurizers and recirculating cooling water systems. (PDF, 10 pp, 517K) Attachments | Curtis Laird | Ecological Effects Branch | - |
06/02/1988 | Dantobrom S and Dantobrom P. EPA ID #s 6836-116 and 6836-118. Acc. Nos. 403313-01 and 403313-07 (PDF, 14 pp, 655K) | Joycelyn Stewart | Toxicology Branch | - |
05/04/1988 | Dantobrom S and Dantobrom P. EPA ID Nos. 6836-116; 6836-118. Acc. Nos. 403313-01 and 403313-07 Tox review 006687 (PDF, 8 pp, 542K) | Joycelyn Stewart | Toxicology Branch | - |
03/03/1988 | 5,5-Dimethylhydantoin and 5-ethyl, 5-methylhydantoin. EPA ID # 38906-3, -4, -7, -9, -12, -13, -14, -15. Tox Chem Nos. 366D, 568E, 309C. Product formulation information on page 1 is not included (PDF, 3 pp, 155K) | Joycelyn Stewart | Toxicology Branch | - |
07/17/1987 | File or Reg. No. 3377-EG, 3377-EE, 3377-EU. Data Review for Technical. Avian acute oral LD50, Bobwhite quail, page 5. Eight-day dietary LC50, Bobwhite, p.9; Mallard, p.12. 96-hour LC50, Bluegill, Fathead, p.15; Trout, p.18. 48-hour LC50 p.22. (PDF, 24 pp, 815K) | Curtis Laird | Ecological Effects Branch | - |
07/07/1987 | Resubmission (Skin Irritation and Eye Irritation Data) (PDF, 4 pp, 140K) | James Wilson | Disinfectants Branch | - |
06/30/1987 | Dantobrom S. EPA ID No. 38906-13 and Dantobrom P, EPA ID No. 38906-15 (PDF, 19 pp, 666K) | Joycelyn Stewart | Toxicology Branch | - |
05/14/1987 | Dantobrom S, EPA ID No. 38906-13 and Dantobrom P, EPA ID No. 38906-15. Commercial/financial information on page 1 is not included Tox review 005876 (PDF, 17 pp, 891K) | Joycelyn Stewart | Toxicology Branch | - |
05/13/1987 | Reg./File No. 8959-44. Registration for use in indoor and outdoor swimming pools. Both the hydrolysis and the aqueous photodegradation studies should be repeated with a purified material... Acc. # 265455 and 265456. (PDF, 4 pp, 193K) | Akiva Abramovitch | Exposure Assessment Branch | - |
05/12/1987 | Registration for Use in Indoor and Outdoor Swimming Pools and Spas (PDF, 4 pp, 206K) | Akiva Abramovitch | Exposure Assessment Branch | - |
05/01/1987 | Reg./File No. 3377-EG, 3377-EE, 3377-EU. Registration for use in swimming pools. (PDF, 8 pp, 356K) | Akiva Abramovitch | Exposure Assessment Branch | - |
02/17/1987 | 8622-EL Registration for use in indoor and outdoor swimming pools and spas Hydrolysis and Photodegradation in Water. Acc. 264468 (PDF, 4 pp, 231K) | James Adams | Exposure Assessment Branch | - |
01/12/1987 | Bromochloro-5,5,dimethylhydantoin; 1-bromo- 3-chloro-5,5-dimethylhydantoin EPA ID# 8622-EL Mutagenicity. Acc. 264468. Tox review 005654 (PDF, 10 pp, 585K) | Joycelyn Stewart | Toxicology Branch | - |
11/26/1986 | Resubmission - Tox Data (PDF, 3 pp, 150K) | James Wilson | Disinfectants Branch | - |
10/31/1985 | Dantobrom, EPA Registration No. 38906-14. Dantobrom P, EPA File Symbol 38906-RL. Data Requirements for Use in Spas and Swimming Pools. Manufacturing process information on page 2 is not included (PDF, 4 pp, 296K) | Joycelyn Stewart | Toxicology Branch | - |
07/15/1985 | 8622-EL New Application Acute Oral, Acute Dermal, Skin Irritation, Eye Irritation Acc. 258165 (PDF, 3 pp, 125K) | James Wilson | Disinfectants Branch | - |
07/11/1985 | 8622-EL Submission of data to support proposed microbicide uses Acc. 258164 (PDF, 2 pp, 84K) | Leslie Touart | Ecological Effects Branch | - |
03/12/1985 | Dantobrom, Dantobrom S, & Dantobrom P Data Requirements for Use in Spas and Swimming Pools - Glycol (PDF, 2 pp, 76K) | Robert Zendzian | Toxicology Branch | - |
02/26/1985 | Review Protocols (Hydrolysis Study) (PDF, 3 pp, 120K) | Samuel Creeger | Exposure Assessment Branch | - |
11/13/1984 | Reg./File No. 8959-UN. Request for waiver from the aqueous photolysis study. (PDF, 3 pp, 129K) | Samuel Creeger | Exposure Assessment Branch | - |
11/06/1984 | File No. 8959-UU. Brominating Compounds. Proposed Registration of Uses in Spas and Hot Tubs (PDF, 24 pp, 879K) | Curtis Laird | Ecological Effects Branch | - |
09/27/1984 | Response to Data Requirements (PDF, 4 pp, 176K) | Samuel Creeger | Exposure Assessment Branch | - |
09/12/1984 | New Product Registration (PDF, 3 pp, 101K) | William Campbell | Disinfectants Branch | - |
09/12/1984 | Reg./File No. 38906-RL use in swimming pools. Discussion of Data. The three active ingredients in the product were... previously reviewed (13 April 1984). Page 6 removed, confidential statement of formula. (PDF, 10 pp, 645K) | Samuel Creeger | Exposure Assessment Branch | - |